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When we were on the books, waiting for a baby with Down syndrome, we were offered a baby with Rubinstein-Taybi syndrome (a lot of similar manifestations as Down syndrome). We said yes and 5 years later they called us about another baby with Rubinstein-Taybi syndrome (we were not planning to adopt again) and we said yes again.
They're both amaziing little boys and we love them dearly.
Janet