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I relinquished my son in 1972, so the agencies may not even operate this way anymore. The way it worked back then, the expectant mother was asked to fill out an extensive list of possible medical problems for herself, the expectant father, her parents, and her siblings.
The thing was, though, that I was 16 years old, so I didn't have a huge medical dossier yet. Both my parents were in their middle 30's, and they had none of the diseases they would get in later life.
Fortunately, I was reunited with my son many years ago, so I supply him with my updated medical history whenever another middle-aged disease crops up. Also, he now has the knowledge of what killed my father, and he knows what caused his grandmother's stroke.
The important thing about medical history of birth parents and their immediate families is that it be updated on a regular basis, since so many birth mothers are young at the time of relinquishment.