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I agree with all that's been said above. Our agency had the birthparents fill out a medical and social history questionnaire. But the truth is a lot of times a birthparent may not know their own medical history that well (they may be young, not know much about their own medical history later on their extended family's medical history, or could even be adopted themselves; and a lot of times you will not even get information about the birthfather).
However, we did look at situations from several agencies before making a decision. And I noticed a lot of variability in how thorough they were. We shied away from a few cases where there were blanket "none" statements with long arrows drawn down an entire column or across a page. Also, there were some cases where the birthmother obviously had not filled out the questionnaire herself, although she had signed that she did.
Our agency did make an effort to obtain records from the few prenatal visits that were done. Again we didn't get a lot of info b/c prenatal care was minimal, but at least there was some info obtained.
In the end, even with all the info we got, it was a leap of faith. You should definitely ask for all the information you can, but also realize that often the information will be minimal at best and may not be that reliable.