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I've fostered multiple drug addicted kids and both my adopted children were prenatally exposed to various things.
ALL of my kids have had some level of trouble from their exposure. That said, they have a lot of other things going on in their birth families histories that make it hard to say what was caused by what.
I would tell you brother in law's sis to be ready for anything as there is just a really wide spectrum of problems that can result... or the baby really could be perfectly fine, but that has not been my experience.
I will say, my daughter's issues are very minor right now, she receives no extra services... she just has some atypical behaviors. My son's issues are extremely challenging, but many different things affect my son's functioning aside from his prenatal exposure.